Review
Nature Reviews Genetics 3, 683-697 (September 2002) | doi:10.1038/nrg889
Article series: The Art and Design of Genetic Screens
The art and design of genetic screens: filamentous fungi
Lorna Casselton1 & Miriam Zolan2 About the authors
Abstract
In the 1940s, screens for metabolic mutants of the filamentous fungus Neurospora crassa established the fundamental, one-to-one relationship between a gene and a specific protein, and also established fungi as important genetic organisms. Today, a wide range of filamentous species, which represents a billion years of evolutionary divergence, is used for experimental studies. The developmental complexity of these fungi sets them apart from unicellular yeasts, and allows the development of new screens that enable us to address biological questions that are relevant to all eukaryotes.
- View At a Glance
Author affiliations
- Department of Plant Sciences, University of Oxford, South Parks Road, Oxford, OX1 3RB, UK
- Department of Biology, Indiana University, 1001 East Third Street, Bloomington, Indiana 47405, USA
Correspondence to: Lorna Casselton1 Email: lorna.casselton@plants.ox.ac.uk
|
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated REFERENCE NEWS AND VIEWS RESEARCH |
