Review
Nature Reviews Genetics 3, 124-136 (February 2002) | doi:10.1038/nrg730
Article series: The Art and Design of Genetic Screens
The art and design of genetic screens: Arabidopsis thaliana
Damian R. Page1 & Ueli Grossniklaus1 About the authors
Abstract
Molecular genetic studies rely on well-characterized organisms that can be easily manipulated. Arabidopsis thaliana — the model system of choice for plant biologists — allows efficient analysis of plant function, combining classical genetics with molecular biology. Although the complete sequence of the Arabidopsis genome allows the rapid discovery of the molecular basis of a characterized mutant, functional characterization of the Arabidopsis genome depends on well-designed forward genetic screens, which remain a powerful strategy to identify genes that are involved in many aspects of the plant life cycle.
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Author affiliations
- Institute of Plant Biology, University of Zürich, Zollikerstrasse 107, CH-8008 Zürich, Switzerland.
Correspondence to: Ueli Grossniklaus1 Email: grossnik@botinst.unizh.ch
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