Review

Nature Reviews Genetics 3, 22-32 (January 2002) | doi:10.1038/nrg701

Subject Category: Multifactorial genetics

Focus on: Multifactorial Genetics

Multifactorial genetics: The use of molecular genetics in the improvement of agricultural populations

Jack C. M. Dekkers1 & Frédéric Hospital2  About the authors

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Substantial advances have been made in the genetic improvement of agriculturally important animal and plant populations through artificial selection on quantitative traits. Most of this selection has been on the basis of observable phenotype, without knowledge of the genetic architecture of the selected characteristics. However, continuing molecular genetic analysis of traits in animal and plant populations is leading to a better understanding of quantitative trait genetics. The genes and genetic markers that are being discovered can be used to enhance the genetic improvement of breeding stock through marker-assisted selection.

Author affiliations

  1. Department of Animal Science, Iowa State University, 225 Kildee Hall, Ames, Iowa 50011, USA.
  2. Station de Génétique Végétale, INRA/UPS/INAPG, Ferme du Moulon, 91190 Gif sur Yvette, France.
    Email: Fred@moulon.inra.fr

Correspondence to: Jack C. M. Dekkers1 Email: j.dekkers@iastate.edu

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