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Nature Reviews Genetics 10, 426–427 (1 July 2009) | doi:10.1038/nrg2623

Transcriptomics: Revealing the extent of RNA editing

Louisa Flintoft

Mammalian RNAs can be edited by the conversion of adenosine to inosine, which is read as guanosine, but technological constraints have limited our view of the overall contribution of RNA editing to transcriptomic diversity. A new method now allows RNA editing sites to be identified genome-wide.