Access

Research Highlights

Nature Reviews Genetics 10, 219 (1 April 2009) | doi:10.1038/nrg2566

Systems genetics: Networking complex traits

Meera Swami

Determining the genetic architecture of complex traits poses a challenge because most phenotypic variation is caused by numerous interactions between a multitude of environmentally sensitive genes. A recent study that uses systems genetics to analyse complex traits in Drosophila melanogaster is an important step towards understanding the complex genetic networks that underpin ecologically relevant phenotypes in this organism.