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Research Highlights

Nature Reviews Genetics 10, 5 (1 January 2009) | doi:10.1038/nrg2513

Human disease: Genome-wide insights into lipid levels

Mary Muers

As for many complex traits, genome-wide association (GWA) studies are revolutionizing the dissection of the genetic determinants of blood lipid levels, a known risk factor for cardiovascular disease. Three recent reports highlight how differences in study design can provide complementary insights and identify novel risk loci that could improve our understanding of lipoprotein metabolism.