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Autoimmunity

Does celiac disease trigger autoimmune thyroiditis?

Nature Reviews Endocrinology volume 5, pages 190–191 (2009)Cite this article

Autoimmune thyroiditis has increased prevalence in patients with celiac disease and vice versa. New research suggests that serum transglutaminase 2 autoantibodies, which are present in patients with celiac disease, might have a role in the development of thyroid dysfunction.

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Figure 1: IgA autoantibodies against transglutaminase 2 present in the sera of patients with active celiac disease bind to this enzyme in thyroid tissue.

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Acknowledgements

I would like to thank Ms Maria Panoutsopoulou for her valuable assistance in the preparation of this manuscript.

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  1. Endocrine Unit, Evgenidion Hospital, University of Athens Medical School, 20 Papadiamantopoulou Street, 115 28 Athens, Greece ledunt@otenet.gr

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  1. Endocrine Unit, Evgenidion Hospital, University of Athens Medical School, Athens, Greece

    Leonidas H. Duntas

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  1. Leonidas H. Duntas
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Duntas, L. Does celiac disease trigger autoimmune thyroiditis?. Nat Rev Endocrinol 5, 190–191 (2009). https://doi.org/10.1038/nrendo.2009.46

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