Gastric banding to treat obesity: band-aid or breakthrough?

Kenneth S Polonsky and Samuel Klein

doi:10.1038/ncpendmet0889 | Full Text | PDF (103K)

Serum adiponectin levels predict progression from diabetic nephropathy to ESRD

doi:10.1038/ncpendmet0873 | Full Text | PDF (91K)

Hyperthyroidism linked with increased ectopic supraventricular heart activity

doi:10.1038/ncpendmet0874 | Full Text | PDF (91K)

LRP5 polymorphisms influence BMD and fracture risk

doi:10.1038/ncpendmet0875 | Full Text | PDF (102K)

Effects of growth hormone therapy in children with PWS

doi:10.1038/ncpendmet0876 | Full Text | PDF (92K)

Beneficial effects of GHRT in women with hypopituitarism

doi:10.1038/ncpendmet0877 | Full Text | PDF (103K)

Use of both IGF and collagen markers could improve detection of GH abuse

doi:10.1038/ncpendmet0878 | Full Text | PDF (91K)

Different vitamin D therapeutic regimens are equally effective in young children

doi:10.1038/ncpendmet0879 | Full Text | PDF (91K)

T₃ thyrotoxicosis in patients with massively metastatic thyroid carcinoma

doi:10.1038/ncpendmet0880 | Full Text | PDF (92K)

Effects of childhood exposure to Chernobyl fallout on thyroid function

doi:10.1038/ncpendmet0881 | Full Text | PDF (92K)

CKD severity in patients with diabetes affects the risk of foot ulcer

doi:10.1038/ncpendmet0882 | Full Text | PDF (103K)

Effects of lowered LDL and blood pressure targets on atherosclerosis and CVD events

doi:10.1038/ncpendmet0883 | Full Text | PDF (93K)

Bisphosphonate use does not increase the risk of atrial fibrillation and flutter

doi:10.1038/ncpendmet0884 | Full Text | PDF (103K)

Effects of metformin or repaglinide therapy for diabetes on serum markers for CVD

doi:10.1038/ncpendmet0885 | Full Text | PDF (93K)

Central obesity in middle age increases the risk of dementia later in life

doi:10.1038/ncpneuro0814 | Full Text | PDF (93K)

Can calcitonin and carcinoembryonic antigen doubling times predict progression of thyroid carcinoma?

Joshua Klopper and Bryan Haugen

doi:10.1038/ncpendmet0865 | Full Text | PDF (130K)

Dietary glycemic index and glycemic load in diabetes prevention—what can we learn from observational studies?

Mark A Pereira

doi:10.1038/ncpendmet0867 | Full Text | PDF (127K)

Is somatic RET mutation a prognostic factor for sporadic medullary thyroid carcinoma?

Jan Zedenius

doi:10.1038/ncpendmet0866 | Full Text | PDF (131K)

Does an intensive multifactorial intervention reduce mortality in type 2 diabetes mellitus?

Bernard Zinman

doi:10.1038/ncpendmet0868 | Full Text | PDF (125K)

Prognostic role of undetectable ablation thyroglobulin and follow-up thyroglobulin in patients with thyroid cancer

Sophie Leboulleux

doi:10.1038/ncpendmet0864 | Full Text | PDF (128K)

The cutting edge in diabetes treatment—is weight-loss surgery an effective therapeutic strategy?

Lee M Kaplan and Nadia N Ahmad

doi:10.1038/ncpendmet0893 | Full Text | PDF (132K)

Are prescribing patterns of antidiabetic medications influenced by fears of litigation?

John B Buse

Management of diabetes mellitus is occasionally confounded by lack of understanding on the part of physicians and patients of issues surrounding the risks and benefits of antidiabetic drugs. The need for adequately powered outcome studies that minimize the effects of the unknown on prescribing habits in diabetes care is debated.

doi:10.1038/ncpendmet0869 | Full Text | PDF (117K)

Dehydroepiandrosterone replacement therapy—panacea, snake oil, or a bit of both?

Alice Y Chang, Hans K Ghayee and Richard J Auchus

Age-related declines in dehydroepiandrosterone sulfate concentration parallel the physical and cognitive changes of aging. This observation suggests that these events are causally related and that replacement therapy might have beneficial effects in the elderly. The authors of this Viewpoint consider the evidence for, and against, such an approach.

doi:10.1038/ncpendmet0870 | Full Text | PDF (126K)

Environmental factors and autoimmune thyroiditis

Leonidas H Duntas

Autoimmune thyroiditis, which manifests as Hashimoto thyroiditis and Graves disease among other forms, is an inflammatory disorder of the thyroid gland. Various environmental factors interact with susceptibility genes and seem to be associated with disease initiation and to influence duration and severity. This Review summarizes the currently available information and highlights the areas that urgently require further study.

doi:10.1038/ncpendmet0896 | Full Text | PDF (201K)

Techniques to quantify TSH receptor antibodies

RA Ajjan and AP Weetman

Thyroid stimulation in Graves disease is caused by antibodies to the TSH receptor that have thyroid-stimulating or thyroid-blocking activity. Antibody detection can aid diagnosis and prediction of outcomes of the disease, as well as prediction of the course of associated ophthalmology. In this Review, Ajjan and Weetman describe the different measurement techniques available and their clinical applications.

doi:10.1038/ncpendmet0886 | Full Text | PDF (248K)