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Nature Reviews Endocrinology 3, 512–513 (1 July 2007) | doi:10.1038/ncpendmet0529

Ovulation induction in polycystic ovary syndrome|[mdash]|how do metformin and clomifene citrate compare?

Marie-H|[eacute]|l|[egrave]|ne Pesant & Jean-Patrice Baillargeon

Neveu N et al. (2007) Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction and achievement of pregnancy in 154 women with polycystic ovary syndrome. Fertil Steril 87: 113–120 Synopsis Background Anovulatory infertility is a key feature of polycystic ovary syndrome (PCOS).