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Nature Reviews Endocrinology 3, 448–449 (1 June 2007) | doi:10.1038/ncpendmet0502

Can dehydroepiandrosterone or testosterone replacement effectively treat the symptoms of aging?

Wiebke Arlt

Nair KS et al. (2006) DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med 355: 1647–1659 Synopsis Background As the levels of anabolic hormones decline with age, replacement therapy could be used to treat age-related changes in physiologic function, such as reduced muscle mass and BMD.