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Nature Reviews Endocrinology 2, 414–415 (1 August 2006) | doi:10.1038/ncpendmet0261

How low to target LDL?

Jennifer G Robinson & Michael H Davidson

According to the National Cholesterol Education Program, an optional LDL goal of less than 1.81 mmol/l might now be considered for patients at the highest risk of coronary heart disease. This Viewpoint discusses whether these LDL target levels are safe and describes which agents might help achieve this goal.