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Nature Reviews Endocrinology 2, 258–259 (1 May 2006) | doi:10.1038/ncpendmet0171

Do markers of bone turnover predict clinical outcome in patients with bone metastases?

Theresa A Guise

Coleman RE et al. (2005) Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid. J Clin Oncol 23: 4925–4935 Synopsis Background Patients with advanced solid tumors frequently experience bone metastases, which increase rates of bone turnover.