Neuroendocrine networks were previously perceived mainly as transcriptionally controlled, neural regulatory pathways that are centred at the hypothalamus. However, multisystemic circuits encompassing the brain and peripheral tissues have now been uncovered that involve nonneuronal cells and nontranscriptional regulatory mechanisms, with previously unidentified functions, such as reward and behaviour. Several developments in 2016 have helped to consolidate these new advances.
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Tena-Sempere, M. Neuroendocrine control of metabolism and reproduction. Nat Rev Endocrinol 13, 67–68 (2017). https://doi.org/10.1038/nrendo.2016.216
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DOI: https://doi.org/10.1038/nrendo.2016.216
