Polycystic ovary syndrome (PCOS) is associated with adverse metabolic and reproductive outcomes and guidelines recommend early diagnosis, screening and management. However, new stricter definitions of the diagnostic features of polycystic ovaries on ultrasonography might in fact exclude some women from a diagnosis of PCOS who could benefit from preventive management.
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References
March, W. A. et al. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Hum. Reprod. 25, 544–551 (2010).
Teede, H. J. et al. Assessment and management of polycystic ovary syndrome: summary of an evidence-based guideline. Med. J. Aust. 195, S65–S112 (2011).
Quinn, M. M. et al. Raising threshold for diagnosis of polycystic ovary syndrome excludes population of patients with metabolic risk. Fertil. Steril. http://dx.doi.org/10.1016/j.fertnstert.2016.06.026 (2016).
Dewailly, D. et al. Definition and significance of polycystic ovarian morphology: a task force report from the Androgen Excess and Polycystic Ovary Syndrome Society. Hum. Reprod. Update 20, 334–352 (2014).
Gibson-Helm, M. E., Lucas, I. M., Boyle, J. A. & Teede, H. J. Women's experiences of polycystic ovary syndrome diagnosis. Fam. Pract. 31, 545–549 (2014).
Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil. Steril. 81, 19–25 (2004).
Kristensen, S. L. et al. A very large proportion of young Danish women have polycystic ovaries: is a revision of the Rotterdam criteria needed? Hum. Reprod. 25, 3117–3122 (2010).
Stepto, N. K. et al. Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp. Hum. Reprod. 28, 777–784 (2013).
Teede, H. J. et al. Longitudinal weight gain in women identified with polycystic ovary syndrome: results of an observational study in young women. Obesity (Silver Spring) 21, 1526–1532 (2013).
Hayes, M. G. et al. Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. Nat. Commun. 6, 7502 (2015).
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Boyle, J., Teede, H. Refining diagnostic features in PCOS to optimize health outcomes. Nat Rev Endocrinol 12, 630–631 (2016). https://doi.org/10.1038/nrendo.2016.157
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DOI: https://doi.org/10.1038/nrendo.2016.157
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