A massive prospective study that assessed the association between consumption of cereals and mortality has concluded that cereal fibre is a component of whole grains that is potentially protective. This focus on cereal fibre is not fully consonant with plant and human biology and might distract from the aspect of most importance in prediction of chronic disease—the whole grain and its myriad bioactive phytochemical constituents.
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References
Wu, H. et al. Association between dietary whole grain intake and risk of mortality: two large prospective studies in US men and women. JAMA Intern. Med. 175, 373–384 (2015).
Jacobs, D. R. Jr & Gallaher, D. D. Whole grain intake and cardiovascular disease: a review. Curr. Atheroscler. Rep. 6, 415–423 (2004).
Huang, T., Xu, M., Lee, A., Cho, S. & Qi, L. Consumption of whole grains and cereal fiber and total and cause-specific mortality: prospective analysis of 367,442 individuals. BMC Med. 13, 59 (2015).
Park, Y., Subar, A. F., Hollenbeck, A. & Schatzkin, A. Dietary fiber intake and mortality in the NIH-AARP diet and health study. Arch. Intern. Med. 171, 1061–1068 (2011).
Jacobs, D. R. Jr, Andersen, L. F. & Blomhoff, R. Whole-grain consumption is associated with a reduced risk of noncardiovascular, noncancer death attributed to inflammatory diseases in the Iowa Women's Health Study. Am. J. Clin. Nutr. 85, 1606–1614 (2007).
Pereira, M. A. et al. Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studies. Arch. Intern. Med. 164, 370–376 (2004).
Goodlad, R. A. & Englyst, H. N. Redefining dietary fibre: potentially a recipe for disaster. Lancet 358, 1833–1834 (2001).
Jacobs, D. R., Pereira, M. A., Meyer, K. A. & Kushi, L. H. Fiber from whole grains, but not refined grains, is inversely associated with all-cause mortality in older women: the Iowa Women's Health Study. J. Am. Coll. Nutr. 19 (3 Suppl.), 326S–330S (2000).
Panel on the Definition of Dietary Fiber and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Dietary reference intakes: proposed definition of dietary fiber (2001). The National Academies Press [online] (2001).
Colaric, M., Veberic, R., Solar, A., Hudina, M. & Stampar, F. Phenolic acids, syringaldehyde, and juglone in fruits of different cultivars of Juglans regia L. J. Agric. Food Chem. 53, 6390–6396 (2005).
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D.R.J.Jr is funded, in part, by a grant from the NIH National Heart, Lung, and Blood Institute, HL R01 53560.
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D.R.J.Jr is a consultant to the California Walnut Commission.
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Jacobs, D. The whole cereal grain is more informative than cereal fibre. Nat Rev Endocrinol 11, 389–390 (2015). https://doi.org/10.1038/nrendo.2015.76
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DOI: https://doi.org/10.1038/nrendo.2015.76
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