Exercise training is one of the key interventions for preventing and treating type 2 diabetes mellitus. Although the health-promoting effects of exercise are largely ascribed to improvements in skeletal muscle insulin sensitivity, new data published in Diabetes suggest 'exercise-trained' subcutaneous adipose tissue might also have an important role in enhancing glucose homeostasis.
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Acknowledgements
The authors acknowledge funding from The Swedish Research Council, European Research Council, Swedish Diabetes Association, Swedish Foundation for Strategic Research, Strategic Diabetes Research Program at Karolinska Institutet, Stockholm County Council and Novo Nordisk Foundation.
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Wallberg-Henriksson, H., Zierath, J. Exercise remodels subcutaneous fat tissue and improves metabolism. Nat Rev Endocrinol 11, 198–200 (2015). https://doi.org/10.1038/nrendo.2015.24
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DOI: https://doi.org/10.1038/nrendo.2015.24
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