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Elevated risk of mortality in type 1 diabetes mellitus

Nature Reviews Endocrinology volume 11, pages 136–138 (2015)Cite this article

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Type 1 diabetes mellitus (T1DM) is associated with increased risk of mortality, despite improvements in management of glucose levels and treatment of cardiovascular risk factors. A population-based study of individuals with T1DM and control individuals matched for age and sex has used glycaemic control to characterize the excess risk of overall and cardiovascular mortality.

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Figure 1: Hazard ratios and attributable risk (per 1,000 person-years) for all-cause mortality (orange) and CVD-associated mortality (turquoise) according to levels of HbA1c among patients with T1DM versus controls.

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Acknowledgements

Support for this work was provided by NIH NHLBI grant HL113029 and JDRF grant 17-2013-313. J.K.S.-B. has also received an American Diabetes Association Career Development Award (7-13-CD-10).

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  1. Barbara Davis Centre for Diabetes, University of Colorado Anschutz Medical Campus, 1775 Aurora Court, Aurora, CO 80045, USA

    Janet K. Snell-Bergeon & David M. Maahs

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  1. Janet K. Snell-Bergeon
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  2. David M. Maahs
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Correspondence to Janet K. Snell-Bergeon.

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Snell-Bergeon, J., Maahs, D. Elevated risk of mortality in type 1 diabetes mellitus. Nat Rev Endocrinol 11, 136–138 (2015). https://doi.org/10.1038/nrendo.2014.245

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