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Nature Reviews Endocrinology 1, 66 (1 December 2005) | doi:10.1038/ncpendmet0037

Hypertension in patients with acromegaly

Caroline Barranco

Vitale G et al. (2005) Hypertension in acromegaly and in the normal population: prevalence and determinants. Clin Endocrinol 63: 470–476 Noncontrolled, small studies have documented the high incidence of hypertension in patients with acromegaly, in whom chronic excess of growth hormone and insulin-like growth factor 1 (IGF-1) contribute to fluid retention and increased cardiovascular mortality rates.