Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Research Highlights
Nature Reviews Drug Discovery 8, 538–539 (1 July 2009) | doi:10.1038/nrd2934
Neurodegenerative disorders: HDAC2 is the one
Abstract
Inhibitors of histone deacetylase (HDAC) enzymes have been shown to improve learning and memory; however, multiple forms of HDAC exist, and the development of more effective HDAC inhibitors would benefit from knowing the specific HDAC(s) that are involved in the regulation of synaptic plasticity. Tsai and colleagues now show that in neurons HDAC2 is responsible.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
