Abstract
Although the first two investigational anti-diabetic drugs to be assessed for increased cardiovascular risk by the US FDA are unlikely to require additional clinical trials before approval, companies are actively adapting their preclinical and clinical development programmes in response to last year's FDA guidance.
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Opar, A. Diabetes drugs pass cardiovascular risk check. Nat Rev Drug Discov 8, 343–344 (2009). https://doi.org/10.1038/nrd2890
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DOI: https://doi.org/10.1038/nrd2890