FIGURE 1 | The top 40 therapeutic/disease areas ranked by the number of trials registered with ClinicalTrials.gov from October 2005 to September 2007.
From the following article:
Trends in disease focus of drug development
Johan P. E. Karlberg
Nature Reviews Drug Discovery 7, 639-640 (August 2008)
doi:10.1038/nrd2618

The 40 areas are ranked according to the proportion of Phase II trials out of all Phase II/III trials. Phase IV trials were not considered here as they are not conducted for all therapeutic areas. ADHD, attention-deficit/hyperactivity disorder; COPD, chronic obstructive pulmonary disorder; ICU, intensive care unit; MS, multiple sclerosis.
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