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Research Highlights
Nature Reviews Drug Discovery 7, 559 (1 July 2008) | doi:10.1038/nrd2630
Eye diseases: Convenient leakage reduction
Abstract
Current available therapies for eye diseases associated with abnormal retinal vascular permeability, such as age-related macular degeneration, require repeated intraocular injection. Now, Scheppke and colleagues, writing in The Journal of Clinical Investigation, describe a tyrosine kinase inhibitor that can be topically applied to reduce vascular leakage in the eye, potentially addressing the delivery-related limitations of existing drugs.
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