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Research Highlights

Nature Reviews Drug Discovery 7, 478 (1 June 2008) | doi:10.1038/nrd2600

Stem cells: Boosting myocardial repair

Bethan Hughes

Stem-cell-based therapy is a promising approach for restoring cardiac function following myocardial infarction and heart failure, with initial trials supporting its feasibility, although efficacy has been limited. Understanding the factors that influence the differentiation of stem cells into desired cardiac cell types is a key challenge to fulfilling the potential of this approach.