Figures and Tables
From the following article:
Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
Paul D. Dobson & Douglas B. Kell
Nature Reviews Drug Discovery 7, 205-220 (March 2008)
doi:10.1038/nrd2438
Figure 1
Transmembrane transport of drugs.
Figure 2
Comparisons between drug permeability in natural membranes and artificial systems, and their comparison with oil–water partition coefficients.
Figure 3
Comparisons between drug permeability in natural membranes and artificial systems, and their comparison with oil–water partition coefficients.
Figure 4
Multiple drug carriers in different tissues, all of which may need to be permeated.
Figure 5
Tissue-selective expression of solute carrier molecules, where brown colouration indicates presence of protein.
Figure 6
The 'bottom-up' systems biology agenda.
Table 1
Some searchable databases for transporter molecules*
Table 2
Overview of the human transporter superfamilies and families with possible/known roles in drug uptake
Table 3
Examples of drug uptake by three of the most significant families of transporter
Table 4
Some common drug substrates of the most prolific SLC transporter families*
