Figures and Tables
From the following article:
Microenvironmental regulation of biomacromolecular therapies
Hyun Joon Kong & David J. Mooney
Nature Reviews Drug Discovery 6, 455-463 (June 2007)
doi:10.1038/nrd2309
Figure 1
The cellular microenvironment varies with tissue injury and pathogenesis.
Figure 2
In vitro cell response to protein drugs is modulated by the microenvironment.
Figure 3
Potential strategies to engineer cell microenvironments in vivo to modulate the cellular response to protein drugs.
Figure 4
In vitro efficiency of gene transfer and subsequent level of expression are modulated by properties of the extracellular matrix (ECM).
