FIGURE 4 | Interaction of 
-N-acetylneuraminic acid (1a) with influenza virus sialidase.
From the following article:
The war against influenza: discovery and development of sialidase inhibitors
Mark von Itzstein
Nature Reviews Drug Discovery 6, 967-974 (December 2007)
doi:10.1038/nrd2400
a | 
-N-acetylneuraminic acid (-Neu5Ac) bound in a boat-like conformation to the influenza virus sialidase active site. b | Eight invariant amino-acid residues make direct contact with Neu5Ac. c | Neu5Ac interactions with the influenza A virus sialidase active site (derived from LIGPLOT software67).
Download file
If the slide opens in your browser, select "File > Save As" to save it.