FIGURE 3 | Chemical structures of selected compounds.

From the following article:

The war against influenza: discovery and development of sialidase inhibitors

Mark von Itzstein

Nature Reviews Drug Discovery 6, 967-974 (December 2007)

doi:10.1038/nrd2400

The war against influenza: discovery and development of sialidase inhibitors

1a, alpha-N-acetylneuraminic acid (alpha-Neu5Ac); 1b, beta-anomer of Neu5Ac; 2a, 2-deoxy 2,3-didehydro Neu5Ac (Neu5Ac2en); 2b, N-trifluoroacetylated derivative of Neu5Ac; 3, 2-deoxy-alpha-Neu5Ac; 4, 4-amino-4-deoxy-NeuAc2en; 5, 4-deoxy-4-guanidino-Neu5Ac2en, now known as zanamivir; 6, azide derivative of 4 and 5; 7, uronic acid; 8, oseltamivir carboxylate (GS 4071); 9, peramivir; 10, a pyrrolidine, A-315675 (Ref. 54); 11, oseltamivir (GS 4104); 12, divalent zanamivir.

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