FIGURE 1 | Replication cycle of HIV with current and possible targets for antiviral intervention.
From the following article:
HIV drug development: the next 25 years
Charles Flexner
Nature Reviews Drug Discovery 6, 959-966 (December 2007)
doi:10.1038/nrd2336
Proteins that are targets for approved drugs are coloured green: gp160, reverse transcriptase, HIV protease and chemokine (C-C motif) receptor 5 (CCR5). Integrase (yellow) is a target in advanced clinical development. Proteins that are more speculative drug targets are coloured red: chemokine (C-X-C motif ) receptor 4 (CXCR4), RNase H, tat, rev, nef and vif.
Download file
If the slide opens in your browser, select "File > Save As" to save it.