Figures and Tables

From the following article:

Multi-targeting by monotherapeutic antibacterials

Lynn L Silver

Nature Reviews Drug Discovery 6, 41-55 (January 2007)

doi:10.1038/nrd2202

Figure 1 - Multi-targeting by monotherapeutic antibacterials

Figure 1

beta-lactam antibiotics.

Figure 2 - Multi-targeting by monotherapeutic antibacterials

Figure 2

Trans-peptidation.

Figure 3 - Multi-targeting by monotherapeutic antibacterials

Figure 3

Reactions of topoisomerases.

Figure 4 - Multi-targeting by monotherapeutic antibacterials

Figure 4

Next-generation compounds overcoming resistance.

Figure 5 - Multi-targeting by monotherapeutic antibacterials

Figure 5

Hybrid and single-target agents overcoming resistance.

Table 1 - Multi-targeting by monotherapeutic antibacterials

Table 1

Characteristics determining the profile of antibacterial compounds

Table 2 - Multi-targeting by monotherapeutic antibacterials

Table 2

Antibacterial compounds commonly used in systemic monotherapy

Table 3 - Multi-targeting by monotherapeutic antibacterials

Table 3

Antibacterials targeting single enzymes in clinical use (excluding mycobacterial infection)

Table 4 - Multi-targeting by monotherapeutic antibacterials

Table 4

Antimycobacterial drugs