FIGURE 2 | Trans-peptidation.
From the following article:
Multi-targeting by monotherapeutic antibacterials
Lynn L Silver
Nature Reviews Drug Discovery 6, 41-55 (January 2007)
doi:10.1038/nrd2202
a | Penicillin is an analogue of D-Ala-D-Ala. The bond broken by transpeptidase activity is indicated by the arrow. b | Lipid II (undecaprenyl-pyrophosphoryl-N-acetylmuramyl-(pentapeptide)-N acetylglucosamine). c | Transpeptidation (crosslinking reaction). Crosslinking of meso-diaminopimelic acid to D-Ala is indicated by the curved arrow.
Download file
If the slide opens in your browser, select "File > Save As" to save it.