Perspective

Nature Reviews Drug Discovery 5, 641-647 (August 2006) | doi:10.1038/nrd2035

EssayApplying the concepts of financial options to stimulate vaccine development

David Brogan1 & Elias Mossialos1  About the authors

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Stimulating research and development for neglected diseases (such as tuberculosis, malaria and AIDS) has proven difficult. We offer an alternative approach to stimulating research into neglected diseases based on the concept of a financial call option. Our Call Options for Vaccines (COV) model allows the purchaser to make payments during the early stages of development in exchange for reduced future prices. We conclude with a discussion of possible risks and benefits.

Author affiliations

  1. David Brogan is a Research Associate in Health Economics, and Elias Mossialos is Professor of Health Policy, at LSE Health, London School of Economics and Political Science, Houghton Street, London WC2A 2AE, United Kingdom.
    Email: d.m.brogan@lse.ac.uk
    Email: e.a.mossialos@lse.ac.uk

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