Figures and Tables

From the following article:

Lipid II as a target for antibiotics

Eefjan Breukink and Ben de Kruijff

Nature Reviews Drug Discovery 5, 321-323 (April 2006)

doi:10.1038/nrd2004

Figure 1 - Lipid II as a target for antibiotics

Figure 1

Schematic presentation of the cell-wall synthesis cycle.

Figure 2 - Lipid II as a target for antibiotics

Figure 2

Structures of antibiotics that target Lipid II.

Figure 3 - Lipid II as a target for antibiotics

Figure 3

Post-translational modifications in nisin.

Figure 4 - Lipid II as a target for antibiotics

Figure 4

Model for the target-directed pore-formation mechanism of nisin.

Figure 5 - Lipid II as a target for antibiotics

Figure 5

Interaction of nisin with Lipid II: the pyrophosphate cage.

Table 1 - Lipid II as a target for antibiotics

Table 1

Activity spectrum and development stage of Lipid-II-interacting compounds