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Nature Reviews Drug Discovery 5, 987–988 (1 December 2006) | doi:10.1038/nrd2204

Panitumumab

Leonard Saltz , Chris Easley & Peter Kirkpatrick

In September 2006, panitumumab (Vectibix; Amgen), a fully human antibody against the epidermal growth factor receptor (EGFR), was approved by the FDA for the treatment of patients with EGFR-expressing metastatic colorectal cancer with disease progression on or following fluoropyrimidine-, oxaliplatin- and irinotecan-containing chemotherapy regimens.