TABLE 1 | Molecular targets of FDA-approved drugs
From the following article:
How many drug targets are there?
John P. Overington, Bissan Al-Lazikani and Andrew L. Hopkins
Nature Reviews Drug Discovery 5, 993-996 (December 2006)
doi:10.1038/nrd2199
| Class of drug target | Species | Number of molecular targets |
|---|---|---|
| Targets of approved drugs | Pathogen and human | 324 |
| Human genome targets of approved drugs | Human | 266 |
| Targets of approved small-molecule drugs | Pathogen and human | 248 |
| Targets of approved small-molecule drugs | Human | 207 |
| Targets of approved oral small-molecule drugs | Pathogen and human | 227 |
| Targets of approved oral small-molecule drugs | Human | 186 |
| Targets of approved therapeutic antibodies | Human | 15 |
| Targets of approved biologicals | Pathogen and human | 76 |
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