Box 1 | Drugs with unknown mechanism of action

From the following article:

Drugs, their targets and the nature and number of drug targets

Peter Imming, Christian Sinning & Achim Meyer

Nature Reviews Drug Discovery 5, 821-834 (October 2006)

doi:10.1038/nrd2132

4-Aminosalicylic acid | Alendronate | Ambroxol | Arsenic trioxide | Becaplermin | Bexarotene | Chloral hydrate | Clofazimine | Dactinomycin (RNA synthesis inhibitor) | Dapsone (folic acid synthesis inhibitor) | Diethyl carbamazine | Diethyl ether | Diloxanide | Dinitric oxide | Ethambutol | Gentian violet | Ginkgolides | Griseofulvin | Halofantrine | Halothane | Hydrazinophthalazine | Limefantrine (antimalarial; prevents haem polymerization) | Levetiracetam | Mebendazole | Methyl-(5-amino-4-oxopentanoate) | Niclosamide | Pentamidine | Podophyllotoxin | Procarbazine | Selenium sulphide