Nature Reviews Drug Discovery 5, 821-834 (October 2006) | doi:10.1038/nrd2132

There is a Corrigendum (1 February 2007) associated with this article.

OpinionDrugs, their targets and the nature and number of drug targets

Peter Imming1, Christian Sinning1 & Achim Meyer1  About the authors


What is a drug target? And how many such targets are there? Here, we consider the nature of drug targets, and by classifying known drug substances on the basis of the discussed principles we provide an estimation of the total number of current drug targets.

Author affiliations

  1. Peter Imming, Christian Sinning and Achim Meyer are at Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, 06120 Halle, Germany.

Correspondence to: Peter Imming1 Email: