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Nature Reviews Drug Discovery 5, 17-18 (January 2006) | doi:10.1038/nrd1933

Fresh from the PipelineNelarabine

Varsha Gandhi1, Michael J. Keating1, Guy Bate2 & Peter Kirkpatrick3

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In October 2005, nelarabine (Arranon; GlaxoSmithKline), a nucleoside analogue, was given accelerated approval by the US FDA for the treatment of patients with T-cell acute lymphoblastic leukaemia and T-cell lymphoblastic lymphoma whose disease has not responded to treatment or has relapsed following treatment with at least two chemotherapy regimens.

Author affiliations

  1. Varsha Gandhi and Michael Keating are at the University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas 77030, USA.
    Email: vgandhi@mdanderson.org
    Email: mkeating@mdanderson.org
  2. Guy Bate is at IMS Health, 7 Harewood Avenue, London NW1 6JB, UK.
    Email: gbate@uk.imshealth.com
  3. Peter Kirkpatrick is at Nature Reviews Drug Discovery, UK.
    Email: p.kirkpatrick@nature.com

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