Table of contents


Editorial: The time is now

p613 | doi:10.1038/nrd1817

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Research Highlights

G-Protein-coupled receptors: It takes two... | PDF (220 KB)

p627 | doi:10.1038/nrd1805

Inflammation: The nerve of macrophages | PDF (195 KB)

p628 | doi:10.1038/nrd1806

RNA interference: Silence of the genes | PDF (391 KB)

p628 | doi:10.1038/nrd1809

Antiviral drugs: Breakthrough for HCV research | PDF (275 KB)

p629 | doi:10.1038/nrd1808

Screening: Won't get fooled again | PDF (173 KB)

p630 | doi:10.1038/nrd1807

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Perspectives

Article series: Model organisms

Opinion

The ultimate model organism: progress in experimental medicine

Bruce H. Littman & Stephen A. Williams

p631 | doi:10.1038/nrd1800

Opinion

Pharmacogenetics-based therapeutic recommendations — ready for clinical practice?

Julia Kirchheiner, Uwe Fuhr & Jürgen Brockmöller

p639 | doi:10.1038/nrd1801

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Reviews

Computer-based de novo design of drug-like molecules

Gisbert Schneider & Uli Fechner

p649 | doi:10.1038/nrd1799

Leukotriene modifiers as potential therapeutics for cardiovascular disease

Colin D. Funk

p664 | doi:10.1038/nrd1796

The vagus nerve and the nicotinic anti-inflammatory pathway

Luis Ulloa

p673 | doi:10.1038/nrd1797

Asymmetry on large scale: the roadmap to stereoselective processes

Hans-Jürgen Federsel

p685 | doi:10.1038/nrd1798

Correction: HDL as a target in the treatment of atherosclerotic cardiovascular disease

Patrick Linsel-Nitschke & Alan R. Tall

| doi:10.1038/nrd1819

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