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Nature Reviews Drug Discovery 4, 809–810 (1 October 2005) | doi:10.1038/nrd1857

Tigecycline

Richard Wenzel , Guy Bate & Peter Kirkpatrick

Tigecycline (Tygacil;Wyeth) was approved by the US FDA for the treatment of a range of bacterial infections in June 2005. It is the first in a new generation of tetracyclines known as glycylcyclines, which have been developed to overcome the problems of resistance to earlier tetracyclines.