Table of contents
October 2005 Vol 4 No 10
In This Issue
p791 | doi:10.1038/nrd1873
Editorial: Risky business
p793 | doi:10.1038/nrd1866
News and Analysis
Animal rights extremism crosses the Atlantic | PDF (133 KB)
p795 | doi:10.1038/nrd1867
PPPs succeeding in tackling neglected diseases | PDF (78 KB)
p796 | doi:10.1038/nrd1868
Groups question existence of metabolic syndrome | PDF (88 KB)
p796 | doi:10.1038/nrd1869
News in Brief
Approvals awaited with baited breath | Pharmaceutical companies cementing presence in vaccines market | Paediatric trials one step closer in Europe | Pharmacogenetic blood test approved | FDA sued over biogenerics | Plan B decision delayed | No evidence for increase in drug withdrawals | NIH loosens ethics restrictions | PDF (270 KB)
p798 | doi:10.1038/nrd1870
News Feature
Painful lessons | PDF (262 KB)
p800 | doi:10.1038/nrd1871
Patent watch
Courts clash on written description | PDF (68 KB)
p804 | doi:10.1038/nrd1860
Patent watch
Good-faith explanation | PDF (74 KB)
p804 | doi:10.1038/nrd1861
Patent primer
Obviousness-type double patenting | PDF (58 KB)
p805 | doi:10.1038/nrd1855
An Audience With
Joanna F. Haas | PDF (64 KB)
p806 | doi:10.1038/nrd1872
From the analyst's couch
Drug discovery alliances | PDF (131 KB)
p807 | doi:10.1038/nrd1856
Fresh from the Pipeline
Tigecycline | PDF (147 KB)
p809 | doi:10.1038/nrd1857
Research Highlights
Inflammation: Cooling the inflammatory response | PDF (137 KB)
p811 | doi:10.1038/nrd1863
Infectious disease: Faster drugs for unknown bugs | PDF (443 KB)
p812 | doi:10.1038/nrd1858
Antimicrobial drugs: Accept some substitutes | PDF (169 KB)
p812 | doi:10.1038/nrd1859
Computational chemistry: Docking on trial | PDF (333 KB)
p813 | doi:10.1038/nrd1862
In brief
Ion Channels | Gene Therapy | Infectious Disease | Anticancer Drugs | PDF (171 KB)
p814 | doi:10.1038/nrd1864
Vaccines: 
-Glucan conjugate provides protection | PDF
(171 KB)
p814 | doi:10.1038/nrd1865
Perspectives
Opinion
Anticipating change in drug development: the emerging era of translational medicine and therapeutics
Garret A. FitzGerald
p815 | doi:10.1038/nrd1849
Essay
The political logic of regulatory error
Daniel Carpenter & Michael M. Ting
p819 | doi:10.1038/nrd1850
Reviews
Predicting in vivo drug interactions from in vitro drug discovery data
Larry C. Wienkers & Timothy G. Heath
p825 | doi:10.1038/nrd1851
Chemokines: Integrators of Pain and Inflammation
Fletcher A. White, Sonia K. Bhangoo & Richard J. Miller
p834 | doi:10.1038/nrd1852
Viral and cellular RNA helicases as antiviral targets
Ann D. Kwong, B. Govinda Rao & Kuan-Teh Jeang
p845 | doi:10.1038/nrd1853
Model organisms: Animal Models of sepsis: setting the stage
Jon A. Buras, Bernhard Holzmann & Michail Sitkovsky
p854 | doi:10.1038/nrd1854
