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Review
Nature Reviews Drug Discovery 3, 673–683 (1 August 2004) | doi:10.1038/nrd1468
Drug repositioning: identifying and developing new uses for existing drugs
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Abstract
Biopharmaceutical companies attempting to increase productivity through novel discovery technologies have fallen short of achieving the desired results. Repositioning existing drugs for new indications could deliver the productivity increases that the industry needs while shifting the locus of production to biotechnology companies. More and more companies are scanning the existing pharmacopoeia for repositioning candidates, and the number of repositioning success stories is increasing.
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