Figures and Tables

From the following article:

Principles for modulation of the nuclear receptor superfamily

Hinrich Gronemeyer, Jan-Åke Gustafsson & Vincent Laudet

Nature Reviews Drug Discovery 3, 950-964 (November 2004)

doi:10.1038/nrd1551

Figure 1 - Principles for modulation of the nuclear receptor superfamily

Figure 1

Nuclear receptors in action.

Figure 2 - Principles for modulation of the nuclear receptor superfamily

Figure 2

Ligand binding induces a conformational change of the ligand-binding domain structure of nuclear receptors.

Figure 3 - Principles for modulation of the nuclear receptor superfamily

Figure 3

Comparative view of the ligand-binding pockets of the oestrogen receptor-alpha and -beta.

Figure 4 - Principles for modulation of the nuclear receptor superfamily

Figure 4

Structural basis of antagonist action.

Table 1 - Principles for modulation of the nuclear receptor superfamily

Table 1

Human nuclear receptors

Table 2 - Principles for modulation of the nuclear receptor superfamily

Table 2

Three divergent residues in the RAR ligand-binding pockets