Table of contents
In this issue
p165 | doi:10.1038/nrd1056
Editorial: Follow the yellow brick road
p167 | doi:10.1038/nrd1057
Research Highlights
Cardiovascular disease: Metabonomics reveals blocked pipes
p169 | doi:10.1038/nrd1048
RNA-targeted drugs: The Essence of correction
p170 | doi:10.1038/nrd1029
Inflammation: Targeting two for the price of one
p170 | doi:10.1038/nrd1052
Structure-based drug design: Can GPCR models work?
p171 | doi:10.1038/nrd1030
Cardiovascular disease: Another string to LXR's bow
p172 | doi:10.1038/nrd1050
Apoptosis: If I had a hammer...
p172 | doi:10.1038/nrd1053
Allergy: Eliminating E from the class
p173 | doi:10.1038/nrd1051
Cancer: Parc keeper
p174 | doi:10.1038/nrd1049
News and Analysis
Patent watch
En Banc — all together now | Erythropoietin gets bloody
p174 | doi:10.1038/nrd1055
From the analyst's couch
The painful reality
p175 | doi:10.1038/nrd1038
Fresh from the Pipeline
Eplerenone
p177 | doi:10.1038/nrd1039
Reviews
Article series: Case Histories
Case history
The development of COX2 inhibitors
Rod J. Flower
p179 | doi:10.1038/nrd1034
ADMET in silico modelling: towards prediction paradise?
Han van de Waterbeemd & Eric Gifford
p192 | doi:10.1038/nrd1032
Article series: Case Histories
Case history
Tamoxifen: a most unlikely pioneering medicine
V. Craig Jordan
p205 | doi:10.1038/nrd1031
Effect of pegylation on pharmaceuticals
J. Milton Harris & Robert B. Chess
p214 | doi:10.1038/nrd1033
Article series: A guide to drug discovery
A guide to drug discovery: Combinatorial compound libraries for drug discovery: an ongoing challenge
H. Mario Geysen, Frank Schoenen, David Wagner & Richard Wagner
p222 | doi:10.1038/nrd1035
Perspectives
Opinion
Biotech's twentieth birthday blues
David Miska
p231 | doi:10.1038/nrd1036
Innovation
Big physics, small doses: the use of AMS and PET in human microdosing of development drugs
Graham Lappin & R. Colin Garner
p233 | doi:10.1038/nrd1037
Correction: Therapeutic antibodies for human disease at the dawn of the twenty-first century
Ole Henrik Brekke & Inger Sandlie
p240 | doi:10.1038/nrd1060
Careers and Recruitment
Analytical jobs for analytical minds
Simon Frantz
p243 | doi:10.1038/nrd1058
