Figures and Tables

From the following article:

A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole

Lars Olbe, Enar Carlsson & Per Lindberg

Nature Reviews Drug Discovery 2, 132-139 (February 2003)

doi:10.1038/nrd1010

Figure 1 - A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole

Figure 1

Chemical milestones in the development of proton-pump inhibitors and the year of synthesis.

Figure 2 - A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole

Figure 2

Proton-pump inhibition.

Figure 3 - A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole

Figure 3

Synthesis of omeprazole and esomeprazole.

Figure 4 - A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole

Figure 4

Effects of racemic omeprazole and its enantiomers.

Figure 5 - A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole

Figure 5

Optimal dosing of esomeprazole.