Figures and Tables

From the following article:

GLIA: A novel drug discovery target for clinical pain

Linda R. Watkins & Steven F. Maier

Nature Reviews Drug Discovery 2, 973-985 (December 2003)

doi:10.1038/nrd1251

Figure 1 - GLIA: A novel drug discovery target for clinical pain

Figure 1

Schematic of pain and pain modulation.

Figure 2 - GLIA: A novel drug discovery target for clinical pain

Figure 2

A historical look at glial involvement in pain.

Figure 3 - GLIA: A novel drug discovery target for clinical pain

Figure 3

Microglia, as well as astrocytes, are activated by manipulations that create enhanced nociception in animal models.

Figure 4 - GLIA: A novel drug discovery target for clinical pain

Figure 4

Neuron-to-glia communication.

Figure 5 - GLIA: A novel drug discovery target for clinical pain

Figure 5

Pro-inflammatory cytokines are constitutively expressed in an inactive precursor form, allowing rapid release.

Figure 6 - GLIA: A novel drug discovery target for clinical pain

Figure 6

One of the newest approaches to the treatment of pathological pain by the control of glial activation.