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Regulators and industry tackle dose-finding issues

Nature Reviews Drug Discovery volume 14, pages 371–372 (2015)Cite this article

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Industry experts ask for regulatory guidelines and assurance on the value of well-designed Phase IIb dose-finding studies to help overcome long-standing resistance to sophisticated dose-finding strategies.

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Figure 1: Pairwise comparisons provide poor dose-finding data.
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  1. Asher Mullard
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Mullard, A. Regulators and industry tackle dose-finding issues. Nat Rev Drug Discov 14, 371–372 (2015). https://doi.org/10.1038/nrd4644

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