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Bispecific antibodies rise again

Amgen's blinatumomab is setting the stage for a bispecific-antibody revival, enabled by new formats that may solve the field's long-standing problems.

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Figure 1: Assorted bispecific formats.
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Garber, K. Bispecific antibodies rise again. Nat Rev Drug Discov 13, 799–801 (2014). https://doi.org/10.1038/nrd4478

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