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Opening the lead generation toolbox

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Early-stage drug discovery is rapidly evolving into an endeavour in which scientific research communities in both the public and private sectors are finding new ways to share knowledge, expertise and resources. Here, we discuss some of the challenges for such collaborations and highlight examples in which traditional barriers such as intellectual property concerns have been addressed.

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Correspondence to Peter B. Simpson or Melvin Reichman.

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Competing interests

P.B.S. is an employee of AstraZeneca and M.R. is an employee of the Lankenau Institute for Medical Research Chemical Genomics Center.

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Johns Hopkins Brain Science Institute NeuroTranslational Program

MedChemica

Open Innovation Drug Discovery

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Simpson, P., Reichman, M. Opening the lead generation toolbox. Nat Rev Drug Discov 13, 3–4 (2014). https://doi.org/10.1038/nrd4202

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