A series of setbacks almost caused the demise of PARP inhibitors, but four companies are now beginning pivotal trials of these agents in breast and ovarian cancer.
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Garber, K. PARP inhibitors bounce back. Nat Rev Drug Discov 12, 725–727 (2013). https://doi.org/10.1038/nrd4147
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DOI: https://doi.org/10.1038/nrd4147