Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • From the Analyst's Couch
  • Published:

Managing the health of early-stage discovery

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Success factors.
Figure 2: Average scores for the ten best- and ten worst-performing laboratories: taken from 60 laboratories.

References

  1. Paul, S. M. et al. How to improve R&D productivity: the pharmaceutical industry's grand challenge. Nature Rev. Drug Discov. 9, 203–215 (2010).

    CAS  Google Scholar 

  2. David, E., Tramontin, T. & Zemmel, Z. Pharmaceutical R&D: the road to positive returns. Nature Rev. Drug Discov. 8, 609–610 (2009).

    Article  CAS  Google Scholar 

  3. Munos, B. Lessons from 60 years of pharmaceutical innovation. Nature Rev. Drug Discov. 8, 959–968 (2009).

    Article  CAS  Google Scholar 

  4. Garnier, J. Rebuilding the R&D engine in big pharma. Harvard Bus. Rev. 86, 68–76 (2008).

    Google Scholar 

  5. Hirsch, J. E. An index to quantify an individual's scientific research output. Proc. Natl Acad. Sci. USA 102, 16569–16572 (2005).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael Edwards.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary information Box S1

Methodology (PDF 240 kb)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Edwards, M., Tramontin, T., Simon, D. et al. Managing the health of early-stage discovery. Nat Rev Drug Discov 10, 171–172 (2011). https://doi.org/10.1038/nrd3388

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrd3388

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing